In clinical and research settings, the measurement of specific biomarkers is crucial for understanding the mechanisms behind diseases, particularly in oncology and tissue function. One such biomarker is Anterior Gradient 2 (AGR2), a protein that plays a critical role in cellular stress response, protein folding, and mucosal barrier maintenance. This protein is gaining attention for its potential involvement in various cancers, particularly gastrointestinal and breast cancer, and its link to cellular growth and differentiation.
What is AGR2?
AGR2 is a member of the protein disulfide isomerase family and is primarily expressed in tissues that undergo rapid turnover, such as the gastrointestinal tract and the lungs. It has been implicated in cancer progression due to its role in promoting cell survival under stress conditions. Elevated levels of AGR2 are often found in cancerous tissues, making it an emerging biomarker for cancer diagnosis and prognosis. Beyond oncology, AGR2 is also involved in the regulation of the mucosal barrier, making it relevant to gastrointestinal diseases and inflammatory conditions.
Why Measure AGR2 Levels?
Monitoring AGR2 levels in biological samples is essential for:
- Cancer Research: AGR2 is being studied as a potential biomarker for various cancers, particularly in gastrointestinal and breast cancers, where its expression is often elevated.
- Gastrointestinal Disorders: AGR2 is involved in maintaining the mucosal barrier, and altered levels can indicate conditions such as inflammatory bowel disease (IBD).
- Cell Stress Response: AGR2 helps cells manage stress, making its measurement valuable for studying cellular responses in disease contexts, particularly in cancer therapy.
The ELISA Kit for Human Anterior Gradient 2 (AGR2): A Reliable Solution
The ELISA Kit for Human Anterior Gradient 2 (AGR2), 96-wells plate offers an effective, high-sensitivity method for detecting and quantifying AGR2 levels in human serum, plasma, and other biological fluids. The sandwich ELISA method ensures high specificity for AGR2, with minimal cross-reactivity, making it an ideal choice for clinical research studies investigating AGR2's role in disease progression. The kit's 96-well format allows for multiple samples to be tested simultaneously, improving efficiency and throughput.
Key Features of the ELISA Kit for AGR2:
- High Sensitivity: Capable of detecting low and high concentrations of AGR2.
- User-Friendly: Ready-to-use reagents with clear, detailed instructions.
- Specificity: Designed to specifically measure AGR2, minimizing interference from other proteins.
- Wide Application: Useful in cancer research, gastrointestinal studies, and cell stress research.
Applications:
- Cancer Diagnostics: Investigate AGR2 expression as a potential biomarker for gastrointestinal and breast cancers.
- Gastrointestinal Research: Explore AGR2's role in the maintenance of the mucosal barrier and its potential as a marker for inflammatory diseases like IBD.
- Cellular Stress Studies: Use AGR2 measurements to study cellular stress responses in disease conditions, particularly cancer.
Why Choose the ELISA Kit for AGR2?
The ELISA Kit for Human Anterior Gradient 2 (AGR2) is a reliable and efficient tool for quantifying AGR2 levels in a variety of research and clinical applications. With its high sensitivity, specificity, and ease of use, this kit is perfect for those studying AGR2’s role in disease progression and cancer research. Click here to learn more about the ELISA Kit for Human Anterior Gradient 2 (AGR2), 96-wells plate.